Differential antibiotic sensitivity determined by the large ribosomal subunit in thermophilic archaea.
نویسندگان
چکیده
Hybrid ribosomes obtained by mixing the ribosomal subunits of the extremely thermophilic archaea Sulfolobus solfataricus and Desulfurococcus mobilis were tested for their sensitivity to selected antibiotics. It is shown that structural differences in the large ribosomal subunits determine qualitatively and quantitatively the patterns of response to alpha-sarcin and paromomycin in these species.
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ورودعنوان ژورنال:
- Journal of bacteriology
دوره 178 11 شماره
صفحات -
تاریخ انتشار 1996